Two extremely popular and innovative injectable approaches to skin rejuvenation have been taking the aesthetics world by storm in recent years.

While both treatments aim to enhance skin texture and appearance and can be an essential tool in your holistic approach to skin rejuvenation, they do so in different ways and therefore have some distinct uses, benefits and indications, despite their perceived similarities.

In this blog we will be breaking down some of the key differences between Polynucleotides and Profhilo to help you choose which treatment may be best for you… spoiler alert: You can have both!

What is the difference between Polynucleotides and Profhilo?

Polynucleotides

Polynucleotides fall under the category of regenerative treatments and work by stimulating cellular function and tissue repair on a cellular level.

The Polynucleotides used in the aesthetic industry are derived from purified salmon or trout DNA. Polynucleotide treatments involve injecting these molecules into the dermis through a combination of techniques (e.g. via a cannula or needle).

When injected, they stimulate the body’s natural healing processes, repair cellular damage, improve skin elasticity and hydration, reduce inflammation and boost collagen. This makes them ideal for those looking to reverse the signs of skin ageing and skin damage.

They can be used to improve skin texture and tone, reduce the appearance of fine lines, and can even be used in the management of hair-loss and scar healing.

Polynucleotides’ hero status in recent months has focused on their ability to safely and naturally enhance the undereye area.

If you fancy a deep dive into polynucleotides, then check out my dedicated blogpost here.

Profhilo

Profhilo, although composed of hyaluronic acid, isn’t actually a dermal filler in the traditional sense. It’s a cutting-edge skin bio-remodelling treatment that uses high concentrations of non-cross-linked hyaluronic acid to hydrate from within, stimulating collagen and elastin production. The result? Supercharged hydration and an overall improved skin tone, texture and elasticity with a reduction in fine lines and a healthy glow.

The treatment involves injecting Profhilo into five specific points of the face, known as the Bio Aesthetic Points, for optimal dispersal and absorption. It can also be used to rejuvenate the face (mid and lower face), neck, decolletage, hands, lower abdominal skin, the skin above the knees and crepey inner, upper arm skin. Neck and body treatments involve 10 injection points into the target areas of skin.

Profhilo’s hero status focuses on its ability to provide intense hydration, stimulate collagen production and improve overall skin quality. It is a fantastic choice for those looking to address skin crepey-ness, dryness and fine lines.

In the table below I we have a head-to-head comparison of the two injectable treatments to help make deciding between the two easier than ever!

Which treatment is better for me - Polynucleotides or Profhilo?

In summary, while both Polynucleotides and Profhilo offer significant benefits for skin rejuvenation, the choice between them very much depends on specific skin concerns, desired outcomes, and individual skin conditions. There is even scope to have both treatments done if you have multiple skin concerns to address as they can have a complimentary effect with each other, although we do recommend having these done at separate sessions.

If you’re feeling ready to take the next step in your skin care journey and explore the benefits of Polynucleotides and Profhilo then book yourself in for a detailed, personalised consultation to discover which treatment can bring out the best in your skin. By discussing your skin concerns and goals with your skin health professional you can choose the treatment that could help to enhance your skin in the best and safest way possible.

Click here to book yourself in for the ultimate glow!